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Gene Ontology Information

Protein Name Hos2p
Description Histone deacetylase and subunit of Set3 and Rpd3L complexes; required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; co-localizes with Cmr1p in nuclear foci in response to DNA damage by MMS
GO Terms:
Biological Process
level 5: chromatin organization external link
level 7: histone deacetylation external link
level 7: negative regulation of meiotic nuclear division external link
level 7: regulation of DNA-templated transcription external link
level 8: regulation of transcription by RNA polymerase II external link
level 8: positive regulation of stress-activated MAPK cascade external link
GO Terms:
Molecular Function
level 3: hydrolase activity external link
level 5: histone deacetylase activity external link
level 6: NAD-independent histone deacetylase activity external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component
level 3: nuclear periphery external link
level 3: cytoplasm external link
level 4: histone deacetylase complex external link
level 4: Set3 complex external link
level 4: Rpd3L-Expanded complex external link
level 5: nucleus external link
External source Open in SGD external link
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