S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Hxk2p
Description	Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1
GO Terms: Biological Process	level 2: metabolic process level 4: carbohydrate metabolic process level 5: carbohydrate phosphorylation level 5: glucose 6-phosphate metabolic process level 5: cellular glucose homeostasis level 5: hexose metabolic process level 6: regulation of cell size level 6: phosphorylation level 6: fructose metabolic process level 6: glucose metabolic process level 6: mannose metabolic process level 6: glycolytic process level 7: fructose import across plasma membrane level 7: negative regulation of apoptotic signaling pathway level 8: regulation of transcription by glucose level 8: glucose import
GO Terms: Molecular Function	level 2: catalytic activity level 3: transferase activity level 4: nucleotide binding level 5: glucose binding level 5: kinase activity level 5: phosphotransferase activity, alcohol group as acceptor level 6: hexokinase activity level 6: ATP binding level 6: glucokinase activity level 7: fructokinase activity level 7: mannokinase activity
GO Terms: Cellular Component	level 3: cytosol level 4: mitochondrion level 5: nucleus level 5: mitochondrial membrane
External source	Open in SGD