S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Spt4p
Description	Spt4p/5p (DSIF) transcription elongation factor complex subunit; the Spt4/5 complex binds to ssRNA in a sequence-specific manner, and along with RNAP I and II has multiple roles regulating transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; localizes to kinetochores and heterochromatin, influencing chromosomal dynamics and silencing; required for transcription through long trinucleotide repeats in ORFs and non-protein coding regions
GO Terms: Biological Process	level 5: intracellular mRNA localization level 5: chromatin organization level 7: mRNA processing level 7: regulation of rRNA processing level 7: regulation of DNA-templated transcription level 8: 7-methylguanosine mRNA capping level 8: negative regulation of autophagy level 8: heterochromatin formation level 8: transcription by RNA polymerase I level 9: regulation of transcription elongation by RNA polymerase II level 9: regulation of transcription-coupled nucleotide-excision repair level 9: positive regulation of DNA-templated transcription, elongation level 10: negative regulation of transcription elongation by RNA polymerase I level 10: positive regulation of transcription elongation by RNA polymerase I level 10: positive regulation of transcription elongation by RNA polymerase II
GO Terms: Molecular Function	level 3: protein-containing complex binding level 3: RNA polymerase I general transcription initiation factor activity level 5: metal ion binding level 6: RNA polymerase II complex binding level 6: single-stranded RNA binding level 7: zinc ion binding level 8: rDNA binding
GO Terms: Cellular Component	level 4: chromosome, centromeric region level 4: kinetochore level 5: nucleus level 5: mating-type region heterochromatin level 5: chromosome level 5: DSIF complex level 5: rDNA heterochromatin
External source	Open in SGD