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Gene Ontology Information

Protein Name Brf1p
Description TFIIIB B-related factor; one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB; mutations in human homolog are associated with autosomal recessive cerebellar-facial-dental syndrome
GO Terms:
Biological Process
level 4: transposon integration external link
level 7: DNA-templated transcription initiation external link
level 8: transcription by RNA polymerase III external link
level 8: transcription preinitiation complex assembly external link
level 8: DNA-templated transcription open complex formation external link
level 9: RNA polymerase III preinitiation complex assembly external link
GO Terms:
Molecular Function
level 3: RNA polymerase III general transcription initiation factor activity external link
level 5: metal ion binding external link
level 5: DNA binding external link
level 6: TBP-class protein binding external link
level 7: zinc ion binding external link
level 7: RNA polymerase III core binding external link
level 7: TFIIIC-class transcription factor complex binding external link
level 9: RNA polymerase III type 3 promoter sequence-specific DNA binding external link
GO Terms:
Cellular Component
level 4: transcription preinitiation complex external link
level 5: nucleus external link
level 5: transcription factor TFIIIB complex external link
External source Open in SGD external link
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