S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Mes1p
Description	Methionyl-tRNA synthetase; forms a complex with Gus1p, a glutamyl-tRNA synthetase, and Arc1p, which increases the catalytic efficiency of both synthetases; involved in the nuclear export of tRNAs; mutations in human ortholog MARS is associated with pediatric pulmonary alveolar proteinosis, interstitial lung and liver disease, and Charcot-Marie-Tooth disease; human MARS gene can complement the yeast null mutant
GO Terms: Biological Process	level 5: translation level 6: tRNA aminoacylation for protein translation level 7: methionyl-tRNA aminoacylation
GO Terms: Molecular Function	level 3: ligase activity level 4: nucleotide binding level 5: aminoacyl-tRNA ligase activity level 6: methionine-tRNA ligase activity level 6: ATP binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytosol level 3: methionyl glutamyl tRNA synthetase complex level 3: cytoplasm level 4: aminoacyl-tRNA synthetase multienzyme complex level 5: cytoplasmic stress granule
External source	Open in SGD