S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Gpa1p
Description	Subunit of G protein involved in pheromone response; GTP-binding alpha subunit of heterotrimeric G protein; negatively regulates mating pathway by sequestering G(beta)gamma and triggering an adaptive response; activates Vps34p at endosome; protein abundance increases in response to DNA replication stress; mutations in human homolog GNAS associated with McCune-Albright syndrome
GO Terms: Biological Process	level 3: karyogamy involved in conjugation with cellular fusion level 3: signal transduction level 3: nuclear migration involved in conjugation with cellular fusion level 4: G protein-coupled receptor signaling pathway level 5: response to pheromone level 5: inositol lipid-mediated signaling level 5: pheromone-dependent signal transduction involved in conjugation with cellular fusion level 7: adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion level 9: regulation of MAPK export from nucleus
GO Terms: Molecular Function	level 4: G-protein beta-subunit binding level 4: G-protein beta/gamma-subunit complex binding level 4: nucleotide binding level 5: G protein-coupled receptor binding level 5: metal ion binding level 6: guanyl nucleotide binding level 6: GTP binding level 8: GTPase activity
GO Terms: Cellular Component	level 3: membrane level 3: cytosol level 4: endosome level 4: plasma membrane level 5: heterotrimeric G-protein complex level 5: endosome membrane
External source	Open in SGD