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Gene Ontology Information

Protein Name Erg11p
Description Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation
GO Terms:
Biological Process
level 4: lipid metabolic process external link
level 5: steroid metabolic process external link
level 5: sterol metabolic process external link
level 6: ergosterol biosynthetic process external link
level 6: sterol biosynthetic process external link
level 6: steroid biosynthetic process external link
GO Terms:
Molecular Function
level 3: oxidoreductase activity external link
level 4: sterol 14-demethylase activity external link
level 4: monooxygenase activity external link
level 4: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen external link
level 5: heme binding external link
level 5: metal ion binding external link
level 7: iron ion binding external link
GO Terms:
Cellular Component
level 3: membrane external link
level 4: integral component of membrane external link
level 4: endoplasmic reticulum external link
level 5: endoplasmic reticulum membrane external link
External source Open in SGD external link
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