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Gene Ontology Information

Protein Name Brl1p
Description Essential nuclear envelope/ER integral membrane protein; interacts and functions with Apq12p and Brr6p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, mRNA nuclear export and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; identified as a dosage suppressor of a temperature sensitive mutation in the major karyopherin, CRM1; homologous to Brr6p
GO Terms:
Biological Process		 level 5: protein transport external link
level 6: nuclear envelope organization external link
level 6: mRNA transport external link
level 6: lipid homeostasis external link
GO Terms:
Molecular Function		 level 1: molecular_function external link
GO Terms:
Cellular Component		 level 3: membrane external link
level 4: nuclear envelope external link
level 4: endoplasmic reticulum external link
level 4: integral component of membrane external link
level 5: nucleus external link
level 5: nuclear membrane external link
External source Open in SGD external link
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