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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Cic1p
Description
Essential protein that interacts with proteasome components; has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles
GO Terms:
Biological Process
level 5:
protein catabolic process
level 6:
ribosome biogenesis
level 7:
maturation of LSU-rRNA
level 8:
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
level 8:
rRNA pseudouridine synthesis
level 8:
cleavage involved in rRNA processing
level 8:
snRNA pseudouridine synthesis
level 9:
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO Terms:
Molecular Function
level 3:
protein-macromolecule adaptor activity
level 4:
proteasome binding
level 5:
RNA binding
level 6:
rRNA binding
level 7:
box H/ACA snoRNA binding
level 7:
large ribosomal subunit rRNA binding
GO Terms:
Cellular Component
level 4:
box H/ACA snoRNP complex
level 4:
proteasome complex
level 5:
preribosome, large subunit precursor
level 5:
nucleus
level 5:
nucleolus
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