S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Trm5p
Description	tRNA(m(1)G37)methyltransferase; methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; localized to both cytoplasm and mitochondria, and modifies both cytoplasmic and mitochondrial tRNAs; mutations in human ortholog TRMT5 are associated with skeletal muscle respiratory chain deficiencies, and trm5 mutations analogous to disease mutations decrease respiration
GO Terms: Biological Process	level 3: methylation level 6: tRNA methylation level 7: tRNA N1-guanine methylation level 7: mitochondrial tRNA methylation level 8: tRNA processing
GO Terms: Molecular Function	level 3: transferase activity level 5: methyltransferase activity level 6: tRNA methyltransferase activity level 8: tRNA (guanine-N1-)-methyltransferase activity level 9: tRNA (guanine(37)-N(1))-methyltransferase activity
GO Terms: Cellular Component	level 3: cytoplasm level 4: mitochondrion level 5: nucleus level 5: mitochondrial matrix
External source	Open in SGD