S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dma1p
Description	Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication
GO Terms: Biological Process	level 3: cell cycle level 3: cell division level 5: mitotic spindle assembly checkpoint signaling level 5: establishment of mitotic spindle orientation level 5: cellular bud neck septin ring organization level 6: protein localization to bud neck level 6: mitotic spindle orientation checkpoint signaling level 7: regulation of formin-nucleated actin cable assembly level 7: septin ring assembly level 8: protein ubiquitination level 8: ubiquitin-dependent protein catabolic process level 9: protein autoubiquitination level 9: negative regulation of septation initiation signaling
GO Terms: Molecular Function	level 3: transferase activity level 5: ubiquitin-protein transferase activity level 5: metal ion binding level 6: ubiquitin protein ligase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cell division site level 3: cytoplasm level 3: cytosol level 4: ubiquitin ligase complex level 5: mitotic spindle pole body
External source	Open in SGD