S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rtt107p
Description	BRCA1 C-terminal domain protein needed for recovery from DNA damage; implicated in Mms22-dependent DNA repair during S phase; involved in recruiting SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress
GO Terms: Biological Process	level 5: DNA double-strand break attachment to nuclear envelope level 5: cellular response to DNA damage stimulus level 6: DNA repair level 7: regulation of DNA double-strand break processing level 7: regulation of DNA damage checkpoint level 7: double-strand break repair level 7: negative regulation of transposition, RNA-mediated
GO Terms: Molecular Function	level 3: chromatin binding
GO Terms: Cellular Component	level 3: cell periphery level 5: nucleus level 6: Cul8-RING ubiquitin ligase complex
External source	Open in SGD