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Gene Ontology Information

Protein Name Prk1p
Description Ser/Thr protein kinase; regulates the organization and function of the actin cytoskeleton; inhibits clathrin-mediated endocytosis; phosphorylates the Pan1p and Sla1p subunits of the Pan1p-Sla1p-End3p complex, resulting in inhibition of complex formation; inhibits Scd5p through phosphorylation; phosphorylates Pan1p-interacting proteins, Ent1/2 and Yap1801/2; negatively regulated through autophosphorylation; functional overlap with ARK1
GO Terms:
Biological Process
level 5: actin filament organization external link
level 6: negative regulation of actin cortical patch assembly external link
level 6: protein phosphorylation external link
level 6: phosphorylation external link
level 6: actin cortical patch assembly external link
level 7: negative regulation of protein-containing complex assembly external link
level 8: negative regulation of clathrin-dependent endocytosis external link
GO Terms:
Molecular Function
level 3: transferase activity external link
level 4: nucleotide binding external link
level 4: protein kinase activity external link
level 5: protein serine/threonine kinase activity external link
level 5: kinase activity external link
level 6: ATP binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 4: mating projection tip external link
level 4: actin cortical patch external link
level 5: cytoskeleton external link
External source Open in SGD external link
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