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Gene Ontology Information

Protein Name Fkh1p
Description Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching
GO Terms:
Biological Process
level 4: donor selection external link
level 6: negative regulation of transcription involved in G1/S transition of mitotic cell cycle external link
level 6: chromatin remodeling external link
level 6: positive regulation of transcription involved in G2/M transition of mitotic cell cycle external link
level 6: negative regulation of transcription involved in G2/M transition of mitotic cell cycle external link
level 7: regulation of DNA-templated transcription external link
level 7: negative regulation of pseudohyphal growth external link
level 8: mRNA 3'-end processing external link
level 8: positive regulation of silent mating-type cassette heterochromatin formation external link
level 8: regulation of transcription by RNA polymerase II external link
level 8: termination of RNA polymerase II transcription external link
level 9: negative regulation of transcription by RNA polymerase II external link
level 9: positive regulation of DNA replication initiation external link
level 10: positive regulation of DNA-templated DNA replication initiation external link
level 10: negative regulation of transcription elongation by RNA polymerase II external link
GO Terms:
Molecular Function
level 3: DNA-binding transcription factor activity external link
level 3: chromatin binding external link
level 4: DNA-binding transcription factor activity, RNA polymerase II-specific external link
level 5: DNA-binding transcription repressor activity, RNA polymerase II-specific external link
level 5: DNA-binding transcription activator activity, RNA polymerase II-specific external link
level 5: DNA binding external link
level 6: sequence-specific DNA binding external link
level 8: DNA replication origin binding external link
level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding external link
level 8: centromeric DNA binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 3: cytosol external link
level 5: nucleus external link
External source Open in SGD external link
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