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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Fkh1p
Description
Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching
GO Terms:
Biological Process
level 4:
donor selection
level 6:
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
level 6:
chromatin remodeling
level 6:
positive regulation of transcription involved in G2/M transition of mitotic cell cycle
level 6:
negative regulation of transcription involved in G2/M transition of mitotic cell cycle
level 7:
regulation of DNA-templated transcription
level 7:
negative regulation of pseudohyphal growth
level 8:
mRNA 3'-end processing
level 8:
positive regulation of silent mating-type cassette heterochromatin formation
level 8:
regulation of transcription by RNA polymerase II
level 8:
termination of RNA polymerase II transcription
level 9:
negative regulation of transcription by RNA polymerase II
level 9:
positive regulation of DNA replication initiation
level 10:
positive regulation of DNA-templated DNA replication initiation
level 10:
negative regulation of transcription elongation by RNA polymerase II
GO Terms:
Molecular Function
level 3:
DNA-binding transcription factor activity
level 3:
chromatin binding
level 4:
DNA-binding transcription factor activity, RNA polymerase II-specific
level 5:
DNA-binding transcription repressor activity, RNA polymerase II-specific
level 5:
DNA-binding transcription activator activity, RNA polymerase II-specific
level 5:
DNA binding
level 6:
sequence-specific DNA binding
level 8:
DNA replication origin binding
level 8:
RNA polymerase II cis-regulatory region sequence-specific DNA binding
level 8:
centromeric DNA binding
GO Terms:
Cellular Component
level 3:
cytoplasm
level 3:
cytosol
level 5:
nucleus
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