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Gene Ontology Information

Protein Name Mad2p
Description Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability
GO Terms:
Biological Process		 level 3: cell cycle external link
level 3: cell division external link
level 5: mitotic spindle assembly checkpoint signaling external link
level 5: mitotic DNA integrity checkpoint signaling external link
level 11: positive regulation of protein autoubiquitination external link
GO Terms:
Molecular Function		 level 3: protein-containing complex binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 3: nucleoplasm external link
level 4: mitotic checkpoint complex external link
level 4: kinetochore external link
level 5: nucleus external link
External source Open in SGD external link
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