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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Smc3p
Description
Subunit of the multiprotein cohesin complex; required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member
GO Terms:
Biological Process
level 3:
cell division
level 3:
cell cycle
level 4:
response to oxidative stress
level 4:
reciprocal meiotic recombination
level 5:
mitotic sister chromatid cohesion
level 5:
synaptonemal complex assembly
level 5:
meiotic sister chromatid cohesion
level 6:
chromosome organization
level 9:
replication-born double-strand break repair via sister chromatid exchange
GO Terms:
Molecular Function
level 3:
ATP hydrolysis activity
level 4:
cohesin loading activity
level 4:
nucleotide binding
level 6:
protein kinase binding
level 6:
double-stranded DNA binding
level 6:
ATP binding
GO Terms:
Cellular Component
level 5:
mitotic cohesin complex
level 5:
nucleus
level 5:
chromosome
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