S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Asf1p
Description	Nucleosome assembly factor; involved in chromatin assembly, disassembly; required for recovery after DSB repair; role in H3K56 acetylation required for expression homeostasis, buffering mRNA synthesis rate against gene dosage changes in S phase; anti-silencing protein, derepresses silent loci when overexpressed; role in regulating Ty1 transposition; relocalizes to cytosol under hypoxia; growth defect of asf1 null is functionally complemented by either human ASF1A or ASF1B
GO Terms: Biological Process	level 4: regulation of catalytic activity level 5: chromatin organization level 6: nucleosome assembly level 6: DNA replication-dependent chromatin assembly level 6: regulation of gene expression level 7: histone acetylation level 8: regulation of protein phosphorylation level 8: subtelomeric heterochromatin formation level 8: histone H2B ubiquitination level 8: nucleosome disassembly level 8: histone exchange level 8: regulation of transcription by RNA polymerase II level 10: positive regulation of transcription elongation by RNA polymerase II level 10: positive regulation of histone acetylation level 10: silent mating-type cassette heterochromatin formation
GO Terms: Molecular Function	level 3: structural constituent of chromatin level 4: histone binding
GO Terms: Cellular Component	level 3: cytosol level 4: chromosome, telomeric region level 5: nucleus
External source	Open in SGD