S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Lsm1p
Description	Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress
GO Terms: Biological Process	level 6: RNA metabolic process level 7: mRNA processing level 7: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay level 8: deadenylation-dependent decapping of nuclear-transcribed mRNA level 8: nuclear-transcribed mRNA catabolic process
GO Terms: Molecular Function	level 3: chromatin binding level 5: RNA binding level 6: RNA cap binding level 6: mRNA binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: ribonucleoprotein complex level 4: Lsm1-7-Pat1 complex level 5: P-body level 5: nucleus
External source	Open in SGD