S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tpk1p
Description	cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication
GO Terms: Biological Process	level 3: cell division level 3: cell cycle level 5: protein kinase A signaling level 6: phosphorylation level 6: protein phosphorylation level 6: protein import into nucleus level 6: Ras protein signal transduction level 7: peptidyl-serine phosphorylation level 8: regulation of macroautophagy level 8: double-strand break repair via nonhomologous end joining level 8: negative regulation of cytoplasmic mRNA processing body assembly
GO Terms: Molecular Function	level 3: transferase activity level 4: nucleotide binding level 4: protein kinase activity level 5: kinase activity level 5: protein serine/threonine kinase activity level 6: ATP binding level 6: AMP-activated protein kinase activity level 7: cAMP-dependent protein kinase activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: chromatin level 4: cAMP-dependent protein kinase complex level 5: nucleus
External source	Open in SGD