S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Set2p
Description	Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia
GO Terms: Biological Process	level 3: methylation level 4: ascospore formation level 6: negative regulation of reciprocal meiotic recombination level 7: DNA-templated transcription termination level 7: histone lysine methylation level 7: DNA-templated transcription elongation level 7: regulation of DNA-templated transcription level 8: transcription-coupled nucleotide-excision repair level 8: histone H3-K36 methylation level 9: regulation of DNA-templated DNA replication initiation level 9: negative regulation of antisense RNA transcription level 10: positive regulation of histone acetylation level 11: negative regulation of histone H3-K9 acetylation level 11: negative regulation of histone H3-K14 acetylation
GO Terms: Molecular Function	level 3: transferase activity level 5: methyltransferase activity level 5: RNA binding level 6: histone-lysine N-methyltransferase activity level 7: histone methyltransferase activity (H3-K36 specific) level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytosol level 3: chromatin level 5: nucleus level 5: chromosome
External source	Open in SGD