S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tdh2p
Description	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2; involved in glycolysis and gluconeogenesis; tetramer that catalyzes reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides are active against a wide variety of wine-related yeasts and bateria; TDH2 has a paralog, TDH3, that arose from the whole genome duplication
GO Terms: Biological Process	level 4: reactive oxygen species metabolic process level 5: apoptotic process level 6: glucose metabolic process level 6: glycolytic process level 7: gluconeogenesis
GO Terms: Molecular Function	level 3: oxidoreductase activity level 4: melatonin binding level 4: promoter-specific chromatin binding level 5: NAD binding level 5: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor level 5: NADP binding level 7: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 4: plasma membrane level 4: mitochondrion level 5: fungal-type cell wall level 5: nucleus level 5: lipid droplet
External source	Open in SGD