S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ess1p
Description	Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants
GO Terms: Biological Process	level 8: termination of RNA polymerase II transcription level 8: positive regulation of RNA polymerase II transcription preinitiation complex assembly level 8: negative regulation of ubiquitin-dependent protein catabolic process level 8: positive regulation of rDNA heterochromatin formation level 9: positive regulation of protein dephosphorylation level 9: negative regulation of transcription by RNA polymerase II level 9: positive regulation of transcription by RNA polymerase II level 9: regulation of phosphorylation of RNA polymerase II C-terminal domain level 10: negative regulation of histone deacetylation
GO Terms: Molecular Function	level 3: isomerase activity level 4: peptidyl-prolyl cis-trans isomerase activity level 6: RNA polymerase II complex binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 5: nucleus
External source	Open in SGD