Yeastract
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Gene Ontology Information

Protein Name Sod1p
Description Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex
GO Terms:
Biological Process
level 5: removal of superoxide radicals external link
level 5: fungal-type cell wall organization external link
level 5: protein stabilization external link
level 5: superoxide metabolic process external link
level 5: positive regulation of DNA-binding transcription factor activity external link
level 7: negative regulation of cellular respiration external link
level 8: cellular zinc ion homeostasis external link
level 9: cellular copper ion homeostasis external link
level 9: positive regulation of transcription by RNA polymerase II external link
GO Terms:
Molecular Function
level 2: antioxidant activity external link
level 3: superoxide dismutase activity external link
level 3: oxidoreductase activity external link
level 5: metal ion binding external link
level 7: zinc ion binding external link
level 7: copper ion binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 3: cytosol external link
level 4: mitochondrion external link
level 5: nucleus external link
level 6: mitochondrial intermembrane space external link
External source Open in SGD external link
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