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Gene Ontology Information

Protein Name Jhd2p
Description JmjC domain family histone demethylase; promotes global demethylation of H3K4 and repression of noncoding intergenic transcription during sporulation; removes methyl groups added by Set1p; negatively regulated by H3K14 acetylation; protein levels regulated by Not4p polyubiquitin-mediated degradation; regulates sporulation timing by extending period of active transcription; regulates rDNA silencing; human homolog is JARID1C
GO Terms:
Biological Process
level 5: chromatin organization external link
level 6: chromatin remodeling external link
level 6: regulation of chromatin organization external link
level 6: rDNA heterochromatin formation external link
level 8: antisense RNA transcript catabolic process external link
level 8: regulation of chromosome condensation external link
level 9: negative regulation of ncRNA transcription associated with protein coding gene TSS/TES external link
level 9: negative regulation of transcription by RNA polymerase II external link
level 9: positive regulation of transcription by RNA polymerase II external link
GO Terms:
Molecular Function
level 3: oxidoreductase activity external link
level 4: dioxygenase activity external link
level 5: histone demethylase activity external link
level 5: metal ion binding external link
level 6: histone H3-methyl-lysine-4 demethylase activity external link
level 6: histone H3-tri/di/monomethyl-lysine-4 demethylase activity external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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