S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ipa1p
Description	Protein implicated in pre-mRNA processing and proteasomal degradation; interacts physically and genetically with mRNA cleavage and polyadenylation factors; mutant is impaired in pre-mRNA cleavage and polyadenylation; associates with several Ub-conjugating enzymes and alters Ub-mediated proteasome activity; localizes to both the nucleus and cytosol; contains a HECT_2 domain; homologous to human ubiquitin-protein ligase, UBE3D, a gene implicated in age-related macular degeneration
GO Terms: Biological Process	level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 8: mRNA polyadenylation level 9: protein monoubiquitination level 9: protein autoubiquitination level 9: protein polyubiquitination level 9: pre-mRNA cleavage required for polyadenylation level 10: negative regulation of protein ubiquitination level 10: positive regulation of mRNA 3'-end processing
GO Terms: Molecular Function	level 4: cyclin binding level 6: ubiquitin conjugating enzyme binding level 6: ubiquitin protein ligase activity
GO Terms: Cellular Component	level 3: cytosol level 4: ubiquitin ligase complex level 5: nucleus
External source	Open in SGD