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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Lhs1p
Description
Molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway
GO Terms:
Biological Process
level 4:
protein refolding
level 5:
chaperone cofactor-dependent protein refolding
level 5:
response to unfolded protein
level 6:
post-translational protein targeting to membrane, translocation
level 6:
cellular response to unfolded protein
GO Terms:
Molecular Function
level 2:
protein folding chaperone
level 3:
ATP-dependent protein folding chaperone
level 3:
hydrolase activity
level 3:
ATP hydrolysis activity
level 4:
unfolded protein binding
level 4:
misfolded protein binding
level 4:
heat shock protein binding
level 4:
nucleotide binding
level 4:
adenyl-nucleotide exchange factor activity
level 6:
ATP binding
GO Terms:
Cellular Component
level 3:
cytoplasm
level 4:
mitochondrion
level 4:
endoplasmic reticulum
level 5:
endoplasmic reticulum lumen
External source
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