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Gene Ontology Information

Protein Name Cue2p
Description Ubiquitin-binding endonuclease involved in mRNA decay; recruited to stalled ribosomes to promote breakdown of transcript body of nuclear-transcribed mRNA with stalls in translation elongation; cleaves mRNA within A site of colliding ribosome; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
GO Terms:
Biological Process		 level 8: mRNA cleavage external link
level 9: nuclear-transcribed mRNA catabolic process, no-go decay external link
GO Terms:
Molecular Function		 level 5: ubiquitin binding external link
level 6: endonuclease activity external link
GO Terms:
Cellular Component		 level 1: cellular_component external link
External source Open in SGD external link
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