S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sld2p
Description	Single-stranded DNA origin-binding and annealing protein; required for initiation of DNA replication; phosphorylated in S phase by cyclin-dependent kinases (Cdks), promoting origin binding, DNA replication and Dpb11p complex formation; component of the preloading complex; binds the Mcm2-7p complex to prevent inappropriate Mcm2-7p interaction with the GINS complex in G1; required for S phase checkpoint; relative distribution to the nucleus increases upon DNA replication stress
GO Terms: Biological Process	level 3: cell cycle level 4: DNA replication preinitiation complex assembly level 5: mitotic DNA replication preinitiation complex assembly level 5: mitotic DNA replication checkpoint signaling level 6: DNA replication level 6: DNA replication initiation level 7: negative regulation of protein-containing complex assembly level 9: double-strand break repair via break-induced replication
GO Terms: Molecular Function	level 6: single-stranded DNA binding level 8: DNA replication origin binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: DNA replication preinitiation complex level 5: nucleus
External source	Open in SGD