S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ctk1p
Description	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13
GO Terms: Biological Process	level 4: translational initiation level 5: positive regulation of translational fidelity level 5: cellular response to DNA damage stimulus level 5: regulation of cell cycle level 5: translation level 6: protein phosphorylation level 6: phosphorylation level 7: phosphorylation of RNA polymerase II C-terminal domain level 7: mRNA processing level 8: transcription elongation by RNA polymerase II promoter level 8: mRNA 3'-end processing level 9: positive regulation of DNA-templated transcription, elongation level 9: positive regulation of transcription by RNA polymerase I level 10: positive regulation of transcription elongation by RNA polymerase II
GO Terms: Molecular Function	level 3: transferase activity level 4: protein kinase activity level 4: cyclin binding level 4: nucleotide binding level 5: protein serine/threonine kinase activity level 5: kinase activity level 6: cyclin-dependent protein serine/threonine kinase activity level 6: ATP binding level 6: RNA polymerase II CTD heptapeptide repeat kinase activity
GO Terms: Cellular Component	level 3: nucleoplasm level 3: cytoplasm level 5: cyclin/CDK positive transcription elongation factor complex level 5: nucleus level 5: nucleolus level 6: CTDK-1 complex level 8: cyclin-dependent protein kinase holoenzyme complex
External source	Open in SGD