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Gene Ontology Information

Protein Name Eap1p
Description eIF4E-associated protein, competes with eIF4G for binding to eIF4E; accelerates mRNA degradation by promoting decapping, facilitated by interaction with eIF4E; essential for Puf5p mediated repression; associates with Puf5p and Dhh1p; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade
GO Terms:
Biological Process		 level 7: mRNA catabolic process external link
level 7: regulation of translation external link
level 8: negative regulation of translation external link
level 8: deadenylation-dependent decapping of nuclear-transcribed mRNA external link
GO Terms:
Molecular Function		 level 4: nucleotide binding external link
level 5: eukaryotic initiation factor 4E binding external link
level 6: ATP binding external link
level 6: mRNA binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 4: polysome external link
level 5: cytoplasmic stress granule external link
External source Open in SGD external link
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