S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dre2p
Description	Component of the cytosolic Fe-S protein assembly (CIA) machinery; contains an Fe-S cluster that receives electrons from NADPH via the action of Tah18p in an early step in the CIA pathway; ortholog of human Ciapin1; protein abundance increases in response to DNA replication stress; inviability of the null mutant is functionally complemented by human CIAPIN1
GO Terms: Biological Process	level 5: iron-sulfur cluster assembly level 5: electron transport chain level 8: negative regulation of nitric oxide biosynthetic process level 8: negative regulation of hydrogen peroxide-mediated programmed cell death
GO Terms: Molecular Function	level 3: protein binding level 4: electron transfer activity level 4: iron-sulfur cluster binding level 5: metal ion binding level 5: 2 iron, 2 sulfur cluster binding level 5: 4 iron, 4 sulfur cluster binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 4: mitochondrion level 6: mitochondrial intermembrane space
External source	Open in SGD