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Gene Ontology Information

Protein Name Hbs1p
Description GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, particularly in 3' UTRs; genetically implicated in mRNA no-go decay; HBS1 has a paralog, SKI7, that arose from the whole genome duplication
GO Terms:
Biological Process
level 5: translation external link
level 6: translational elongation external link
level 7: regulation of translation external link
level 7: ribosome disassembly external link
level 8: positive regulation of translation external link
level 9: nonfunctional rRNA decay external link
level 9: nuclear-transcribed mRNA catabolic process, no-go decay external link
GO Terms:
Molecular Function
level 4: nucleotide binding external link
level 5: ribosome binding external link
level 5: translation elongation factor activity external link
level 6: GTP binding external link
level 8: GTPase activity external link
GO Terms:
Cellular Component
level 3: cytosol external link
level 3: Dom34-Hbs1 complex external link
level 3: cytoplasm external link
External source Open in SGD external link
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