S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Prp16p
Description	DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa
GO Terms: Biological Process	level 7: generation of catalytic spliceosome for second transesterification step level 7: mRNA processing level 7: RNA exon ligation level 7: RNA splicing level 7: snRNA modification level 8: mRNA splicing, via spliceosome level 8: snRNA metabolic process
GO Terms: Molecular Function	level 3: ATP-dependent activity, acting on RNA level 3: hydrolase activity level 3: helicase activity level 4: nucleic acid binding level 4: RNA helicase activity level 4: nucleotide binding level 5: second spliceosomal transesterification activity level 5: RNA binding level 6: ATP binding
GO Terms: Cellular Component	level 4: spliceosomal complex level 5: U2-type catalytic step 2 spliceosome level 5: nucleus
External source	Open in SGD