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Gene Ontology Information

Protein Name Oma1p
Description Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults, preservation of normal mitochondrial function under damage-eliciting conditions, and stability of respiratory supercomplexes; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; zebrafish ortholog has a role in organ development and mouse ortholog is also required for respiratory supercomplex stability
GO Terms:
Biological Process
level 3: response to redox state external link
level 5: TOR signaling external link
level 5: proteolysis external link
level 6: mitochondrial protein catabolic process external link
level 6: proteolysis involved in protein catabolic process external link
level 7: mitochondrial protein processing external link
level 7: protein quality control for misfolded or incompletely synthesized proteins external link
GO Terms:
Molecular Function
level 3: hydrolase activity external link
level 4: peptidase activity external link
level 5: metallopeptidase activity external link
level 5: metal ion binding external link
level 6: metalloendopeptidase activity external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component
level 3: membrane external link
level 4: integral component of membrane external link
level 4: mitochondrion external link
level 6: mitochondrial inner membrane external link
External source Open in SGD external link
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