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Gene Ontology Information

Protein Name Isa1p
Description Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa2p and possibly Iba57p; isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources; functional ortholog of bacterial A-type ISC proteins; human ISCA1 can complement isa1 null mutant
GO Terms:
Biological Process		 level 5: iron-sulfur cluster assembly external link
level 6: protein maturation by iron-sulfur cluster transfer external link
level 6: biotin biosynthetic process external link
level 7: protein maturation by [4Fe-4S] cluster transfer external link
GO Terms:
Molecular Function		 level 4: iron-sulfur cluster binding external link
level 5: metal ion binding external link
level 5: 2 iron, 2 sulfur cluster binding external link
level 7: iron ion binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 4: mitochondrion external link
level 5: mitochondrial matrix external link
External source Open in SGD external link
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