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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Bre2p
Description
Subunit of COMPASS (Set1C) complex; COMPASS methylates Lys4 of histone H3 and functions in silencing at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction (SDI) domain that mediates binding to Sdc1p; similar to trithorax-group protein ASH2L
GO Terms:
Biological Process
level 6:
telomere maintenance
level 8:
subtelomeric heterochromatin formation
level 8:
histone H3-K4 methylation
level 8:
histone H3-K4 trimethylation
GO Terms:
Molecular Function
level 6:
transcription cis-regulatory region binding
level 7:
histone methyltransferase activity (H3-K4 specific)
GO Terms:
Cellular Component
level 4:
chromosome, telomeric region
level 5:
chromosome
level 5:
Set1C/COMPASS complex
level 5:
nucleus
External source
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