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Gene Ontology Information

Protein Name Sdo1p
Description Guanine nucleotide exchange factor (GEF) for Ria1p; essential protein involved in ribosome maturation; with Ria1p, promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archaea and eukaryotes
GO Terms:
Biological Process		 level 4: regulation of catalytic activity external link
level 6: ribosome biogenesis external link
level 8: mature ribosome assembly external link
GO Terms:
Molecular Function		 level 6: guanyl-nucleotide exchange factor activity external link
level 7: rRNA primary transcript binding external link
level 7: large ribosomal subunit rRNA binding external link
level 7: small ribosomal subunit rRNA binding external link
level 7: 5.8S rRNA binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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