S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Usb1p
Description	Putative poly(U)-specific 3'-to-5' RNA exonuclease; involved in 3'-end processing of U6 snRNA removing uridines and generating a terminal 2′,3′ cyclic phosphate; essential protein that localizes to the nucleus and mitochondria; overexpression suppresses the respiratory defects of oxa1 and mtf2 mutants; homolog of S.pombe gene, mpn1 and human gene, hUSB1; mutations in hUSB1 are associated with a rare genodermatosis, poikiloderma with neutropenia (OMIM 604173)
GO Terms: Biological Process	level 6: nucleic acid phosphodiester bond hydrolysis level 8: RNA phosphodiester bond hydrolysis, exonucleolytic level 9: U6 snRNA 3'-end processing
GO Terms: Molecular Function	level 3: hydrolase activity level 3: lyase activity level 5: nuclease activity level 8: 3'-5'-exoribonuclease activity level 9: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends
GO Terms: Cellular Component	level 3: cytoplasm level 4: mitochondrion level 5: nucleus
External source	Open in SGD