S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Slx4p
Description	Endonuclease involved in processing DNA; acts during recombination, repair; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); cleaves branched structures in complex with Slx1p; involved in interstrand cross-link repair, Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing; relative distribution to nuclear foci increases upon DNA replication stress; FANCP-related factor
GO Terms: Biological Process	level 3: regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination level 5: cellular response to DNA damage stimulus level 6: DNA replication level 6: DNA repair level 6: DNA recombination level 7: regulation of DNA damage checkpoint level 7: DNA-templated DNA replication level 7: interstrand cross-link repair level 7: double-strand break repair via single-strand annealing, removal of nonhomologous ends level 7: regulation of DNA double-strand break processing level 9: double-strand break repair via break-induced replication
GO Terms: Molecular Function	level 8: 5'-flap endonuclease activity
GO Terms: Cellular Component	level 3: cytoplasm level 4: Slx1-Slx4 complex level 5: nucleus
External source	Open in SGD