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Gene Ontology Information

Protein Name Tis11p
Description mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 5: response to iron ion starvation external link
level 8: nuclear-transcribed mRNA catabolic process external link
level 9: cellular iron ion homeostasis external link
GO Terms:
Molecular Function		 level 3: translation repressor activity external link
level 5: metal ion binding external link
level 5: RNA binding external link
level 6: mRNA binding external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: P-body external link
level 5: nucleus external link
External source Open in SGD external link
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