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Gene Ontology Information

Protein Name Est1p
Description TLC1 RNA-associated factor involved in telomere length regulation; recruitment subunit of telomerase; has G-quadruplex promoting activity required for telomere elongation; role in activating telomere-bound Est2p-TLC1-RNA; EST1 has a paralog, EBS1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 6: G-quadruplex DNA formation external link
level 6: telomere maintenance external link
level 8: telomere maintenance via telomerase external link
level 8: regulation of telomere maintenance via telomerase external link
GO Terms:
Molecular Function		 level 5: DNA binding external link
level 5: RNA binding external link
level 6: single-stranded DNA binding external link
level 7: telomeric DNA binding external link
GO Terms:
Cellular Component		 level 4: chromosome, telomeric region external link
level 4: telomerase holoenzyme complex external link
level 5: nucleus external link
level 5: chromosome external link
level 5: nucleolus external link
External source Open in SGD external link
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