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Gene Ontology Information

Protein Name Top3p
Description DNA Topoisomerase III; conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially; DNA catenation/decatenation activity is stimulated by RPA and Sgs1p-Top3p-Rmi1p; involved in telomere stability and regulation of mitotic recombination
GO Terms:
Biological Process
level 4: reciprocal meiotic recombination external link
level 5: mitotic sister chromatid cohesion external link
level 6: DNA topological change external link
level 7: regulation of DNA recombination external link
level 7: telomere maintenance via recombination external link
level 8: telomere maintenance via telomerase external link
GO Terms:
Molecular Function
level 3: isomerase activity external link
level 4: DNA topoisomerase activity external link
level 5: DNA binding external link
level 5: DNA topoisomerase type I (single strand cut, ATP-independent) activity external link
GO Terms:
Cellular Component
level 4: RecQ family helicase-topoisomerase III complex external link
level 5: nucleus external link
External source Open in SGD external link
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