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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Hsp60p
Description
Tetradecameric mitochondrial chaperonin; required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated
GO Terms:
Biological Process
level 3:
protein folding
level 4:
'de novo' protein folding
level 4:
protein refolding
level 5:
protein stabilization
level 5:
protein maturation
level 5:
protein import into mitochondrial intermembrane space
level 6:
apoptotic mitochondrial changes
level 7:
chaperone-mediated protein complex assembly
level 7:
mitochondrial genome maintenance
level 7:
mitochondrial unfolded protein response
GO Terms:
Molecular Function
level 3:
ATP-dependent protein folding chaperone
level 3:
ATP hydrolysis activity
level 4:
unfolded protein binding
level 4:
chaperone binding
level 4:
nucleotide binding
level 6:
single-stranded DNA binding
level 6:
ATP binding
level 8:
DNA replication origin binding
GO Terms:
Cellular Component
level 4:
mitochondrion
level 4:
mitochondrial nucleoid
level 5:
mitochondrial matrix
level 6:
mitochondrial inner membrane
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