S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Aco1p
Description	Aconitase; required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy; mutation in human homolog ACO2 is associated with dominant optic nerve atrophy; human homolog ACO2 can complement yeast null mutant
GO Terms: Biological Process	level 4: tricarboxylic acid cycle level 7: mitochondrial genome maintenance
GO Terms: Molecular Function	level 3: lyase activity level 4: iron-sulfur cluster binding level 5: 4 iron, 4 sulfur cluster binding level 5: metal ion binding level 6: mRNA binding level 6: aconitate hydratase activity level 6: double-stranded DNA binding level 6: single-stranded DNA binding level 6: citrate dehydratase activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 4: mitochondrion level 4: mitochondrial nucleoid level 5: mitochondrial matrix
External source	Open in SGD