S.cerevisiae - Yeastract

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Gene Ontology Information

Protein Name	Est2p
Description	Reverse transcriptase subunit of the telomerase holoenzyme; essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia
GO Terms: Biological Process	level 8: telomere maintenance via telomerase
GO Terms: Molecular Function	level 3: transferase activity level 5: metal ion binding level 5: nucleotidyltransferase activity level 5: DNA binding level 6: telomerase RNA binding level 6: RNA-directed DNA polymerase activity level 7: telomerase activity level 7: telomerase RNA reverse transcriptase activity level 7: telomeric DNA binding
GO Terms: Cellular Component	level 4: telomerase holoenzyme complex level 4: chromosome, telomeric region level 5: nucleus level 5: chromosome level 5: nucleolus level 5: telomerase catalytic core complex
External source	Open in SGD

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