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Gene Ontology Information

Protein Name Fpr4p
Description Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers
GO Terms:
Biological Process		 level 6: nucleosome assembly external link
level 7: histone peptidyl-prolyl isomerization external link
level 8: negative regulation of histone H3-K36 methylation external link
GO Terms:
Molecular Function		 level 3: isomerase activity external link
level 4: peptidyl-prolyl cis-trans isomerase activity external link
level 4: macrolide binding external link
GO Terms:
Cellular Component		 level 3: chromatin external link
level 5: nucleus external link
level 5: nucleolus external link
External source Open in SGD external link
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