S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Yap1p
Description	Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication
GO Terms: Biological Process	level 4: response to heat level 5: response to singlet oxygen level 6: regulation of endoplasmic reticulum unfolded protein response level 6: response to cadmium ion level 6: positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance level 7: regulation of DNA-templated transcription level 7: positive regulation of transcription from RNA polymerase II promoter in response to stress level 8: regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 3: DNA-binding transcription factor activity level 5: DNA-binding transcription activator activity, RNA polymerase II-specific level 5: DNA binding level 6: transcription cis-regulatory region binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: RNA polymerase II transcription regulator complex level 5: nucleus
External source	Open in SGD