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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Ogg1p
Description
Nuclear and mitochondrial glycosylase/lyase; specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance
GO Terms:
Biological Process
level 2:
metabolic process
level 5:
cellular response to DNA damage stimulus
level 6:
DNA repair
level 6:
base-excision repair, AP site formation
level 7:
nucleotide-excision repair
level 7:
base-excision repair
level 8:
telomere maintenance via telomerase
level 9:
error-free translesion synthesis
GO Terms:
Molecular Function
level 2:
catalytic activity
level 3:
hydrolase activity
level 3:
lyase activity
level 4:
hydrolase activity, acting on glycosyl bonds
level 5:
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
level 6:
damaged DNA binding
level 7:
oxidized purine nucleobase lesion DNA N-glycosylase activity
level 8:
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
GO Terms:
Cellular Component
level 4:
mitochondrion
level 5:
nucleus
External source
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