S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tcb3p
Description	Cortical ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact
GO Terms: Biological Process	level 5: endoplasmic reticulum-plasma membrane tethering level 5: lipid transport level 6: regulation of phosphatidylinositol dephosphorylation level 6: endoplasmic reticulum membrane organization level 6: ER to Golgi ceramide transport
GO Terms: Molecular Function	level 3: lipid binding level 5: calcium-dependent phospholipid binding level 5: metal ion binding
GO Terms: Cellular Component	level 3: cellular bud level 3: membrane level 4: endoplasmic reticulum level 4: plasma membrane level 4: integral component of membrane level 4: mitochondrion level 5: endoplasmic reticulum membrane level 5: cortical endoplasmic reticulum
External source	Open in SGD