S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Vps9p
Description	Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain
GO Terms: Biological Process	level 4: regulation of catalytic activity level 5: vesicle-mediated transport level 6: protein targeting to vacuole level 6: Golgi to endosome transport level 7: late endosome to vacuole transport via multivesicular body sorting pathway level 7: vacuole inheritance level 7: protein localization to endosome
GO Terms: Molecular Function	level 5: ubiquitin binding level 6: small GTPase binding level 6: guanyl-nucleotide exchange factor activity
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 5: endocytic vesicle level 5: early endosome
External source	Open in SGD